Cardinals make decision on Kyler Murray for Week 6

Cardinals Make Decision on Kyler Murray for Week 6

The Arizona Cardinals are preparing for at least a week without Kyler Murray due to a mid-foot sprain.

Murray's status for Sunday's game against the Indianapolis Colts was in jeopardy, but according to ESPN's Adam Schefter, the Cardinals will start backup QB Jacoby Brissett in his place.

Cardinals QB Jacoby Brissett is expected to start Sunday in place of Kyler Murray, who is dealing with a foot injury.

Brissett will make his first start for the Cardinals against the Colts, a team he played for from 2017-2020. The Cardinals have a 2-3 record heading into their Week 6 matchup against the 4-1 Colts.

Author's summary: Cardinals to start Jacoby Brissett over injured Kyler Murray.

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Larry Brown Sports Larry Brown Sports — 2025-10-12