Recent research indicates that individuals with insomnia who take melatonin supplements for over a year may face an increased risk of heart failure compared to those who do not use the sleep aid.
The study found that long-term melatonin users were more likely to:
This research was presented at the American Heart Association’s Scientific Sessions 2025 in New Orleans, though it has not yet been published in a peer-reviewed journal.
The researchers emphasized that their findings do not prove a direct cause-and-effect link between melatonin supplementation and heart failure risk.
Nevertheless, they highlighted that the results raise important safety concerns regarding long-term melatonin use and suggest the need for further cardiovascular safety studies.
Many melatonin supplements are available over-the-counter without a prescription, leading to unregulated use without medical supervision.
“Melatonin supplements may not be as harmless as commonly assumed.”
Long-term melatonin use may pose cardiovascular risks, underscoring the need for more research and cautious use under medical guidance.