Following the tightening of Italy's rules on ancestry-based citizenship, individuals with an Italian parent or grandparent are still eligible to apply for Italian citizenship by descent.
According to the current rules, only those with a direct Italian ancestor, such as a parent or grandparent, can apply for ius sanguinis Italian citizenship.
For individuals born outside Italy, the law is more restrictive, requiring at least one parent or grandparent who holds only Italian citizenship to be eligible.
Only people with an Italian parent or grandparent are eligible to apply for ancestry-based or ius sanguinis Italian citizenship.
Author's summary: Italian citizenship via ancestry is available to those with Italian parents or grandparents.